Tenecteplase (TNK-t PA)
Each vial with lyophilized powder contains the following active pharmaceutical ingredient:
Elaxim 50: 50 mg of Tecnecteplase (recombinant plasminogen tissue activator).
Elaxim is indicated for the thrombolytic treatment of the acute myocardial infarction (AMI) to reduce the mortality associated with AMI.
Therapy with TNK-t-PA in patients with acute myocardial infarction is contraindicated in the following situations because of an increased risk of bleeding:
- Active internal bleeding
- History of stroke
- Intracranial or intraspinal surgery or trauma within two months
- Intracranial neoplasm, arteriovenous malformation or aneurysm
- Known bleeding diathesis
- Severe uncontrolled hypertension
- Hypersensitivity to TNK-t-PA
Elaxim 50: box containing one vial with lyophilized powder + one vial with 8 mL of solvent + syringe.